Splice

2009 · Directed by Vincenzo Natali

Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named Dren, the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators - only to have that bond turn deadly.

horror sci-fi thriller

Cast: Adrien Brody, Sarah Polley, David Hewlett, Amanda Brugel, Delphine Chanéac, Abigail Chu, Simona Măicănescu, Brandon McGibbon, Stephanie Baird

Rating: 5.8/10 from 1,870 votes